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Antivirals, such as acyclovir, famciclovir, and valacyclovir are the most effective medications available for people infected with HSV. The absence of symptoms does not mean the virus cannot be transmitted to others. WHO and partners are working to accelerate research to develop new strategies for prevention and control of genital and neonatal HSV-1 and HSV-2 infections. Genital Herpes. How could genital herpes affect my baby? It cannot tell you who gave you the infection or how long you have been infected.